Rat SIRT2(Sirtuin 2) ELISA Kit

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 2 (SIRT2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 2 (SIRT2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 2 (SIRT2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 2 (SIRT2) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Sirtuin 2 (SIRT2) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: A sandwich ELISA kit for detection of Sirtuin 2 from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Sirtuin 2 (SIRT2) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Sirtuin 2 (SIRT2) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Sirtuin 2 (SIRT2) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Sirtuin 2 (SIRT2) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Sirtuin 2 (SIRT2) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: Recombinant Human Sirtuin 2 expressed in: E.coli

Description: Recombinant Mouse Sirtuin 2 expressed in: E.coli

Description: Recombinant Rat Sirtuin 2 expressed in: E.coli

Description: A sandwich ELISA kit for detection of Sirtuin 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: A sandwich ELISA kit for quantitative measurement of Human SIRT2 (Sirtuin 2) in samples from Serum, Plasma, Cell supernatant

Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.188 ng/ml

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2)

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2)

Description: Quantitative sandwich ELISA for measuring Rat NAD-dependent deacetylase sirtuin-2 (SIRT2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Rat NAD-dependent deacetylase sirtuin-2 (SIRT2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Rat NAD-dependent deacetylase sirtuin-2 (SIRT2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: SIRT2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 372 amino acids (1-352a.a.) and having a molecular mass of 41.7kDa.;SIRT2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with PE.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with PE.

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SIRT2 / Sirtuin 2 (C-Terminus). This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SIRT2 / Sirtuin 2 (N-Terminus). This antibody is tested and proven to work in the following applications:

Description: Rabbit Monoclonal SIRT2/Sirtuin 2 Antibody. Validated in WB and tested in Human, Rat.

Description: Rabbit Monoclonal SIRT2/Sirtuin 2 Antibody. Validated in IP, IF, WB and tested in Human, Rat.

Description: A Rabbit polyclonal antibody against Human, Mouse Sirtuin 2 (SIRT2)

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with APC-Cy7.

Description: A Rabbit polyclonal antibody against Mouse, Rat Sirtuin 2 (SIRT2). This antibody is labeled with APC-Cy7.

Description: A Rabbit polyclonal antibody against Human, Mouse Sirtuin 2 (SIRT2). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Human, Mouse Sirtuin 2 (SIRT2). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Human, Mouse Sirtuin 2 (SIRT2). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Human, Mouse Sirtuin 2 (SIRT2). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Human, Mouse Sirtuin 2 (SIRT2). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Human, Mouse Sirtuin 2 (SIRT2). This antibody is labeled with PE.

Description: Quantitative sandwich ELISA for measuring Human NAD-dependent deacetylase sirtuin-2 (SIRT2/SIR2L/SIR2L2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human NAD-dependent deacetylase sirtuin-2 (SIRT2/SIR2L/SIR2L2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human NAD-dependent deacetylase sirtuin-2 (SIRT2/SIR2L/SIR2L2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: A Rabbit polyclonal antibody against Human, Mouse Sirtuin 2 (SIRT2). This antibody is labeled with APC-Cy7.

Description: ELISA kit for detection of Sirtuin 2 in the research laboratory

Description: Description of target: NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors. Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Functions in the antephase checkpoint preventing precocious mitotic entry in response to microtubule stress agents, and hence allowing proper inheritance of chromosomes. Positively regulates the anaphase promoting complex/cyclosome (APC/C) ubiquitin ligase complex activity by deacetylating CDC20 and FZR1, then allowing progression through mitosis. Associates with both chromatin at transcriptional start sites (TSSs) and enhancers of active genes. Plays a role in cell cycle and chromatin compaction through epigenetic modulation of the regulation of histone H4 'Lys-20' methylation (H4K20me1) during early mitosis. Specifically deacetylates histone H4 at 'Lys-16' (H4K16ac) between the G2/M transition and metaphase enabling H4K20me1 deposition by KMT5A leading to ulterior levels of H4K20me2 and H4K20me3 deposition throughout cell cycle, and mitotic S-phase progression. Deacetylates KMT5A modulating KMT5A chromatin localization during the mitotic stress response. Deacetylates also histone H3 at 'Lys-57' (H3K56ac) during the mitotic G2/M transition. During oocyte meiosis progression, may deacetylate histone H4 at 'Lys-16' (H4K16ac) and alpha-tubulin, regulating spindle assembly and chromosome alignment by influencing microtubule dynamics and kinetochore function. Deacetylates alpha-tubulin at 'Lys-40' and hence controls neuronal motility, oligodendroglial cell arbor projection processes and proliferation of non-neuronal cells. Phosphorylation at Ser-330 by a G1/S-specific cyclin E-CDK2 complex inactivates SIRT2-mediated alpha-tubulin deacetylation, negatively regulating cell adhesion, cell migration and neurite outgrowth during neuronal differentiation. Deacetylates PARD3 and participates in the regulation of Schwann cell peripheral myelination formation during early postnatal development and during postinjury remyelination. Involved in several cellular metabolic pathways. Plays a role in the regulation of blood glucose homeostasis by deacetylating and stabilizing phosphoenolpyruvate carboxykinase PCK1 activity in response to low nutrient availability. Acts as a key regulator in the pentose phosphate pathway (PPP) by deacetylating and activating the glucose-6-phosphate G6PD enzyme, and therefore, stimulates the production of cytosolic NADPH to counteract oxidative damage. Maintains energy homeostasis in response to nutrient deprivation as well as energy expenditure by inhibiting adipogenesis and promoting lipolysis. Attenuates adipocyte differentiation by deacetylating and promoting FOXO1 interaction to PPARG and subsequent repression of PPARG-dependent transcriptional activity. Plays a role in the regulation of lysosome-mediated degradation of protein aggregates by autophagy in neuronal cells. Deacetylates FOXO1 in response to oxidative stress or serum deprivation, thereby negatively regulating FOXO1-mediated autophagy. Deacetylates a broad range of transcription factors and co-regulators regulating target gene expression. Deacetylates transcriptional factor FOXO3 stimulating the ubiquitin ligase SCF(SKP2)-mediated FOXO3 ubiquitination and degradation. Deacetylates HIF1A and therefore promotes HIF1A degradation and inhibition of HIF1A transcriptional activity in tumor cells in response to hypoxia. Deacetylates RELA in the cytoplasm inhibiting NF-kappaB-dependent transcription activation upon TNF-alpha stimulation. Inhibits transcriptional activation by deacetylating p53/TP53 and EP300. Deacetylates also EIF5A. Functions as a negative regulator on oxidative stress-tolerance in response to anoxia-reoxygenation conditions. Plays a role as tumor suppressor.3 Publications;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.157 ng/mL

Description: Description of target: NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors. Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Functions in the antephase checkpoint preventing precocious mitotic entry in response to microtubule stress agents, and hence allowing proper inheritance of chromosomes. Positively regulates the anaphase promoting complex/cyclosome (APC/C) ubiquitin ligase complex activity by deacetylating CDC20 and FZR1, then allowing progression through mitosis. Associates with both chromatin at transcriptional start sites (TSSs) and enhancers of active genes. Plays a role in cell cycle and chromatin compaction through epigenetic modulation of the regulation of histone H4 'Lys-20' methylation (H4K20me1) during early mitosis. Specifically deacetylates histone H4 at 'Lys-16' (H4K16ac) between the G2/M transition and metaphase enabling H4K20me1 deposition by KMT5A leading to ulterior levels of H4K20me2 and H4K20me3 deposition throughout cell cycle, and mitotic S-phase progression. Deacetylates KMT5A modulating KMT5A chromatin localization during the mitotic stress response. Deacetylates also histone H3 at 'Lys-57' (H3K56ac) during the mitotic G2/M transition. During oocyte meiosis progression, may deacetylate histone H4 at 'Lys-16' (H4K16ac) and alpha-tubulin, regulating spindle assembly and chromosome alignment by influencing microtubule dynamics and kinetochore function. Deacetylates alpha-tubulin at 'Lys-40' and hence controls neuronal motility, oligodendroglial cell arbor projection processes and proliferation of non-neuronal cells. Phosphorylation at Ser-330 by a G1/S-specific cyclin E-CDK2 complex inactivates SIRT2-mediated alpha-tubulin deacetylation, negatively regulating cell adhesion, cell migration and neurite outgrowth during neuronal differentiation. Deacetylates PARD3 and participates in the regulation of Schwann cell peripheral myelination formation during early postnatal development and during postinjury remyelination. Involved in several cellular metabolic pathways. Plays a role in the regulation of blood glucose homeostasis by deacetylating and stabilizing phosphoenolpyruvate carboxykinase PCK1 activity in response to low nutrient availability. Acts as a key regulator in the pentose phosphate pathway (PPP) by deacetylating and activating the glucose-6-phosphate G6PD enzyme, and therefore, stimulates the production of cytosolic NADPH to counteract oxidative damage. Maintains energy homeostasis in response to nutrient deprivation as well as energy expenditure by inhibiting adipogenesis and promoting lipolysis. Attenuates adipocyte differentiation by deacetylating and promoting FOXO1 interaction to PPARG and subsequent repression of PPARG-dependent transcriptional activity. Plays a role in the regulation of lysosome-mediated degradation of protein aggregates by autophagy in neuronal cells. Deacetylates FOXO1 in response to oxidative stress or serum deprivation, thereby negatively regulating FOXO1-mediated autophagy. Deacetylates a broad range of transcription factors and co-regulators regulating target gene expression. Deacetylates transcriptional factor FOXO3 stimulating the ubiquitin ligase SCF(SKP2)-mediated FOXO3 ubiquitination and degradation. Deacetylates HIF1A and therefore promotes HIF1A degradation and inhibition of HIF1A transcriptional activity in tumor cells in response to hypoxia. Deacetylates RELA in the cytoplasm inhibiting NF-kappaB-dependent transcription activation upon TNF-alpha stimulation. Inhibits transcriptional activation by deacetylating p53/TP53 and EP300. Deacetylates also EIF5A. Functions as a negative regulator on oxidative stress-tolerance in response to anoxia-reoxygenation conditions. Plays a role as tumor suppressor.3 Publications;Species reactivity: Rat;Application: ELISA;Assay info: ;Sensitivity: < 0.66ng/mL

Description: A competitive ELISA for quantitative measurement of Rat SIRTUIN-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat SIRTUIN-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat SIRTUIN-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat SIRTUIN-6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat SIRTUIN-6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat SIRTUIN-6 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat Sirtuin 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat Sirtuin 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rat Sirtuin 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: Enzyme-linked immunosorbent assay kit for quantification of Rat NAD-dependent deacetylase sirtuin-2 in samples from serum, plasma, tissue homogenates and other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Sirtuin 1 (SIRT1) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Sirtuin 1 (SIRT1) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Sirtuin 3 (SIRT3) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Sirtuin 3 (SIRT3) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 1 (SIRT1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 1 (SIRT1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 1 (SIRT1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Sirtuin 1 (SIRT1) in Tissue homogenates, cell lysates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Sirtuin 1 (SIRT1) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.